Efficacy of linezolid on Treponema pallidum, the syphilis agent: A preclinical study
نویسندگان
چکیده
منابع مشابه
Studies on Treponema Pallidum and Syphilis
Although antibodies can be produced by the immunization of animals with cultivated Treponema pallidum, and although these antibodies exert specific agglutinative and treponemicidal action upon the culture organisms, they possess, at least in the concentration so far obtained by us in rabbits and sheep, practically no action for virulent treponemata obtained directly from lesions. There seems to...
متن کاملAgglutination of Treponema Pallidum in Human Syphilis
The results observed with this strain of Treponema pallidum may be stated as follows: 1. Normal human serum did not agglutinate this culture of Treponema pallidum in dilutions of 1:5 or higher; equal parts of treponema culture and normal serum (dilution 1:2) resulted in agglutination in about 50 per cent of the sera. With the strain of Treponema pallidum used in this study specific agglutinatio...
متن کاملThe genome of Treponema pallidum: new light on the agent of syphilis.
Treponema pallidum subsp, pallidum, the causative agent of the sexually transmitted disease syphilis, is a fastidious, microaerophilic obligate parasite of humans. This bacterium is one of the few prominent infectious agents that has not been cultured continuously in vitro and consequently relatively little is known about its virulence mechanisms at the molecular level. T. pallidum therefore re...
متن کاملStudies on Treponema Pallidum and Syphilis. Ii. Spiroch~ticidal Antibodies against Treponema Pallidum. by Hans
In a previous communication we have reported on the agglufinins which are formed in rabbits following systematic inoculation with concentrated culture material of Treponema pallidum. Incidentally it may be stated that a sheep has also been successfully used. The antigen used for the immunization of these animals was similar to that employed in the first agglutination experiments, except that we...
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ژورنال
عنوان ژورنال: EBioMedicine
سال: 2021
ISSN: 2352-3964
DOI: 10.1016/j.ebiom.2021.103281